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验证数据展示

  • IF Staining of human tonsillitis using CL488-67317

    IF Staining of human tonsillitis using CL488-67317

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite® Plus 488 TLR8 antibody (CL488-67317, Clone: 3B6A4 ) at dilution of 1:200.

  • IF Staining of human tonsillitis using CL488-67317

    IF Staining of human tonsillitis using CL488-67317

    Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite® Plus 488 TLR8 antibody (CL488-67317, Clone: 3B6A4 ) at dilution of 1:200.

CoraLite® Plus 488-conjugated TLR8 Monoclonal antibody

TLR8 Monoclonal Antibody for IF-P
Cat No. CL488-67317

产品说明书

CloneNo. 3B6A4

宿主/亚型

Mouse / IgG1

种属反应性

Human

应用

IF-P

别名

CD288, TLR8, toll like receptor 8

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite® Plus 488
规格价格库存

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经过测试的应用

Positive IF-P detected inhuman tonsillitis tissue
For other applications, we recommend the unconjugated version of this antibody, 67317-1-Ig

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL488-67317 targets TLR8 in IF-P applications and shows reactivity with Human samples.

经测试应用 IF-P Application Description
经测试反应性 Human
免疫原

CatNo: Ag16566

Product name: Recombinant human TLR8 protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 261-610 aa of BC101075

Sequence: FNAPFPCVPCDGGASINIDRFAFQNLTQLRYLNLSSTSLRKINAAWFKNMPHLKVLDLEFNYLVGEIASGAFLTMLPRLEILDLSFNYIKGSYPQHINISRNFSKLLSLRALHLRGYVFQELREDDFQPLMQLPNLSTINLGINFIKQIDFKLFQNFSNLEIIYLSENRISPLVKDTRQSYANSSSFQRHIRKRRSTDFEFDPHSNFYHFTRPLIKPQCAAYGKALDLSLNSIFFIGPNQFENLPDIACLNLSANSNAQVLSGTEFSAIPHVKYLDLTNNRLDFDNASALTELSDLEVLDLSYNSHYFRIAGVTHHLEFIQNFTNLKVLNLSHNNIYTLTDKYNLESKSL

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 toll-like receptor 8
别名 CD288, TLR8, toll like receptor 8
计算分子量 1041 aa, 120 kDa
观测分子量 120 kDa
GenBank蛋白编号BC101075
基因名称 TLR8
Gene ID (NCBI) 51311
RRIDAB_2919451
偶联类型 CoraLite® Plus 488 Fluorescent Dye
最大激发/发射波长493 nm / 522 nm
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ9NR97
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

Toll-like receptors (TLRs) are a group of pathogen recognition receptors (PRRs) that can be divided into two subfamilies depending on their subcellular localization(PMID: 32268138). Toll-like receptor 8 (TLR8), a sensor for pathogen-derived single-stranded RNA (ssRNA), binds to uridine (Uri) and ssRNA to induce defense responses (PMID:30535046). TLR8 proteins were expressed in spleen, epididymal sperm, testicular sperm cells, and Leydig cells but were weak in Sertoli cells. It can identify two isoforms,120 and 122 kDa.

实验方案

Product Specific Protocols
IF protocol for CL Plus 488 TLR8 antibody CL488-67317Download protocol
Standard Protocols
Click here to view our Standard Protocols