• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

验证数据展示

  • IF Staining of MCF-7 using CL555-51067

    IF Staining of MCF-7 using CL555-51067

    Immunofluorescent analysis of (4% PFA) fixed MCF-7 cells using CoraLite®555 Beta Catenin antibody (CL555-51067) at dilution of 1:200.

  • IF Staining of human liver cancer using CL555-51067

    IF Staining of human liver cancer using CL555-51067

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite®555 Beta Catenin antibody (CL555-51067) at dilution of 1:100, CoraLite® Plus 647 CD3 antibody (CL647-60181, Clone: 3F3A1, Magenta), CoraLite® Plus 488 CD163 antibody (CL488-16646, green).

  • IF Staining of human liver cancer using CL555-51067

    IF Staining of human liver cancer using CL555-51067

    Immunofluorescent analysis of (4% PFA) fixed human liver cancer tissue using CoraLite®555 Beta Catenin antibody (CL555-51067) at dilution of 1:100, CoraLite® Plus 647 CD3 antibody (CL647-60181, Clone: 3F3A1, Magenta), CoraLite® Plus 488 CD163 antibody (CL488-16646, green).

  • Featured Product
  • KD/KO验证

CoraLite®555-conjugated Beta Catenin Polyclonal antibody

Beta Catenin Polyclonal Antibody for IF/ICC, IF-P
Cat No. CL555-51067

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

IF/ICC, IF-P

别名

b cat, B-catenin, beta-Catenin, Catenin beta 1, Catenin beta-1

缓冲液配方:  PBS and Azide
PBS and Azide
偶联物:  CoraLite®555
规格价格库存

点击咨询售前客服

点击咨询售后客服

经过测试的应用

Positive IF-P detected inhuman liver cancer tissue
Positive IF/ICC detected inMCF-7 cells
Planning an IHC experiment? We recommend our IHCeasy Beta Catenin Ready-To-Use IHC Kit. Beta Catenin primary antibody included.

推荐稀释比

应用推荐稀释比
Immunofluorescence (IF)-PIF-P : 1:50-1:500
Immunofluorescence (IF)/ICCIF/ICC : 1:50-1:500
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, Check data in validation data gallery.

产品信息

CL555-51067 targets Beta Catenin in IF/ICC, IF-P applications and shows reactivity with human samples.

经测试应用 IF/ICC, IF-P Application Description
经测试反应性 human
免疫原

fusion protein

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 catenin (cadherin-associated protein), beta 1, 88kDa
别名 b cat, B-catenin, beta-Catenin, Catenin beta 1, Catenin beta-1
计算分子量 781 aa, 86 kDa
观测分子量 92 kDa
GenBank蛋白编号BC058926
基因名称 Beta Catenin
Gene ID (NCBI) 1499
ENSEMBL Gene IDENSG00000168036
RRIDAB_2919653
偶联类型 CoraLite®555 Fluorescent Dye
最大激发/发射波长557 nm / 570 nm
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDP35222
储存缓冲液 PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA, pH 7.3.
储存条件Store at -20°C. Avoid exposure to light. Stable for one year after shipment. Aliquoting is unnecessary for -20oC storage.

背景介绍

β-Catenin, also known as CTNNB1, is an evolutionarily conserved, multifunctional intracellular protein. β-Catenin is a 92-kDa protein, originally identified in cell adherens junctions (AJs) where it functions to bridge the cytoplasmic domain of cadherins to a-catenin and the actin cytoskeleton. Besides its essential role in the AJs, β-catenin is also a key downstream component of the canonical Wnt pathway that plays diverse and critical roles in embryonic development and adult tissue homeostasis. The Wnt/β-catenin pathway is also involved in the activation of other intracellular messengers such as calcium fluxes, JNK, and SRC kinases. Deregulation of β-catenin activity is associated with multiple diseases including cancers. (PMID: 22617422; 18334222)

实验方案

Product Specific Protocols
IF protocol for CL555 Beta Catenin antibody CL555-51067Download protocol
Standard Protocols
Click here to view our Standard Protocols