验证数据展示
| Neutralization |
产品信息
69004-1-Ig targets NeutraKine® IL-3 in Neutralization, ELISA applications and shows reactivity with human samples.
| 经测试应用 | Neutralization, ELISA Application Description |
| 经测试反应性 | human |
| 免疫原 | fusion protein 种属同源性预测 |
| 宿主/亚型 | Mouse / IgG1 |
| 抗体类别 | Monoclonal |
| 产品类型 | Antibody |
| 全称 | interleukin 3 (colony-stimulating factor, multiple) |
| 别名 | IL3, IL-3, 3C11G7, IL 3, Interleukin 3 |
| 基因名称 | IL-3 |
| Gene ID (NCBI) | 3562 |
| RRID | AB_2882922 |
| 偶联类型 | Unconjugated |
| 形式 | Lyophilized Powder |
| 纯化方式 | Protein G purification |
| UNIPROT ID | P08700 |
| 储存缓冲液 | Sterile PBS, pH 7.4. |
| 内毒素 | <0.1 EU/μg |
| 复溶 | This product was lyophilized from a 0.2 μm filtered solution in PBS. Reconstitute at 1.0 mg/mL in sterile H2O before use. |
| 稳定性与储存 | Lyophilized antibodies are stable for 1 year from the date of receipt if stored between (-20°C) and (-80°C). Upon reconstitution we recommend that the solution can be stored at (4°C) for short term or at (-20°C) to (-80°C) for long term. Repeated freeze thaw cycles should be avoided with reconstituted products. |
背景介绍
Interleukin-3 (IL-3) is a multilineage hematopoietic growth factor that promotes the proliferation, differentiation and survival of early multilineage hematopoietic progenitors. In particular, this cytokine plays a key role in stimulating the proliferation and survival of myeloid precursors. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders (PMID: 24103757;2698876;2809196).
This antibody can be used to neutralize the bioactivity of IL-3.