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验证数据展示

  • Neutralization experiment of NeutraKine® IL-3 using 69004-1-Ig (same clone as 69004-1-PBS)

    Neutralization experiment of NeutraKine® IL-3 using 69004-1-Ig (same clone as 69004-1-PBS)

    Recombinant human IL-3 (Cat.NO. HZ-1074) stimulates proliferation of TF-1 cell line (human erythroleukemic cell line) in a dose-dependent manner (blue curve, refer to bottom X-left Y). The activity of human IL-3 (10 ng/mL HZ-1074) is neutralized by mouse anti-human IL-3 monoclonal antibody 69004-1-Ig at serial dose (red curve, refer to top X-right Y). The ND50 is typically 40-70 ng/mL. This data was developed using the same antibody clone with 69004-1-PBS in a different storage buffer formulation.

  • Neutralization experiment of NeutraKine® IL-3 using 69004-1-Ig (same clone as 69004-1-PBS)

    Neutralization experiment of NeutraKine® IL-3 using 69004-1-Ig (same clone as 69004-1-PBS)

    Recombinant human IL-3 (Cat.NO. HZ-1074) stimulates proliferation of TF-1 cell line (human erythroleukemic cell line) in a dose-dependent manner (blue curve, refer to bottom X-left Y). The activity of human IL-3 (0.5 ng/mL HZ-1074) is neutralized by mouse anti-human IL-3 monoclonal antibody 69004-1-Ig at serial dose (red curve, refer to top X-right Y). The ND50 is typically 0.8-2.4 ng/mL. This data was developed using the same antibody clone with 69004-1-PBS in a different storage buffer formulation.

NeutraKine® IL-3 Monoclonal antibody, PBS Only

NeutraKine® IL-3 Monoclonal Antibody for Neutralization, ELISA
Cat No. 69004-1-PBS

产品说明书

CloneNo. 3C11G7

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

Neutralization, ELISA

别名

IL3, IL-3, 3C11G7, IL 3, Interleukin 3

缓冲液配方:  PBS Only
Sterile PBS
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

69004-1-PBS targets NeutraKine® IL-3 in Neutralization, ELISA applications and shows reactivity with human samples.

经测试应用 Neutralization, ELISA Application Description
经测试反应性 human
免疫原

Recombinant Protein

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 interleukin 3 (colony-stimulating factor, multiple)
别名 IL3, IL-3, 3C11G7, IL 3, Interleukin 3
基因名称 IL-3
Gene ID (NCBI) 3562
偶联类型 Unconjugated
纯化方式Protein G purification
UNIPROT IDP08700
储存缓冲液 PBS only, pH 7.3.
储存Store at -80°C.

背景介绍

Interleukin-3 (IL-3) is a multilineage hematopoietic growth factor that promotes the proliferation, differentiation and survival of early multilineage hematopoietic progenitors. In particular, this cytokine plays a key role in stimulating the proliferation and survival of myeloid precursors. It is involved in a variety of cell activities such as cell growth, differentiation and apoptosis. This cytokine has been shown to also possess neurotrophic activity, and it may be associated with neurologic disorders (PMID: 24103757;2698876;2809196).

This antibody can be used to neutralize the bioactivity of IL-3.

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