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验证数据展示

  • WB analysis using 60333-1-Ig (same clone as 60333-1-PBS)

    WB analysis using 60333-1-Ig (same clone as 60333-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 60333-1-Ig (TMEM106B antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60333-1-PBS in a different storage buffer formulation.

  • WB analysis of HeLa using 60333-1-Ig (same clone as 60333-1-PBS)

    WB analysis of HeLa using 60333-1-Ig (same clone as 60333-1-PBS)

    WB result of TMEM106B antibody (60333-1-Ig; 1:2000; room temperature for 1.5 hours) with wild-type and TMEM106B knockout HeLa cells. This data was developed using the same antibody clone with 60333-1-PBS in a different storage buffer formulation.

  • IP experiment of HeLa using 60333-1-Ig (same clone as 60333-1-PBS)

    IP experiment of HeLa using 60333-1-Ig (same clone as 60333-1-PBS)

    IP result of anti-TMEM106B (IP:60333-1-Ig, 5ug; Detection:60333-1-Ig 1:500) with HeLa cells lysate 1720 ug. This data was developed using the same antibody clone with 60333-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

TMEM106B Monoclonal antibody, PBS Only

TMEM106B Monoclonal Antibody for WB, IP, Indirect ELISA
Cat No. 60333-1-PBS

产品说明书

CloneNo. 5D1F8

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

WB, IP, Indirect ELISA

别名

TMEM106B (1-46aa), 5D1F8, Transmembrane protein 106B

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

60333-1-PBS targets TMEM106B in WB, IP, Indirect ELISA applications and shows reactivity with human samples.

经测试应用 WB, IP, Indirect ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag21448

Product name: Recombinant human TMEM106B protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 1-46 aa of BC033901

Sequence: MGKSLSHLPLHSSKEDAYDGVTSENMRNGLVNSEVHNEDGRNGDVS

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 transmembrane protein 106B
别名 TMEM106B (1-46aa), 5D1F8, Transmembrane protein 106B
计算分子量 31 kDa
观测分子量 ~40 kDa
GenBank蛋白编号BC033901
基因名称 TMEM106B
Gene ID (NCBI) 54664
RRIDAB_2881442
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDQ9NUM4
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

TMEM106B is a genetic risk factor for frontotemporal lobar degeneration with TDP-43 inclusions (FTLD-TDP). Amyotrophic lateral sclerosis (ALS), like FTLD-TDP, is characterized by pathological TDP-43 inclusions. TMEM106B expression in the brain may be linked to mechanisms of disease in FTLD-TDP and risk alleles confer genetic susceptibility by increasing gene expression.