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验证数据展示

  • IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:9900 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PR antibody included
  • IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:9900 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PR antibody included
  • IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    IHC staining of human breast cancer using 66300-1-Ig (same clone as 66300-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 66300-1-Ig (Progesterone Receptor antibody) at dilution of 1:10000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 66300-1-PBS in a different storage buffer formulation.

    Ready-to-use IHC kits available with PR antibody included

Progesterone Receptor Monoclonal antibody, PBS Only

Progesterone Receptor Monoclonal Antibody for IHC, ELISA
Cat No. 66300-1-PBS

产品说明书

CloneNo. 3D1D12

宿主/亚型

Mouse / IgG1

种属反应性

human

应用

IHC, ELISA

别名

PGR, 3D1D12, NR3C3, PR, PRGR

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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Planning an IHC experiment? We recommend our IHCeasy PR Ready-To-Use IHC Kit. PR primary antibody included.

产品信息

66300-1-PBS targets Progesterone Receptor in IHC, ELISA applications and shows reactivity with human samples.

经测试应用 IHC, ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag22992

Product name: Recombinant human PR protein

Source: e coli.-derived, PET28a

Tag: 6*His

Domain: 1-301 aa of NM_000926

Sequence: MTELKAKGPRAPHVAGGPPSPEVGSPLLCRPAAGPFPGSQTSDTLPEVSAIPISLDGLLFPRPCQGQDPSDEKTQDQQSLSDVEGAYSRAEATRGAGGSSSSPPEKDSGLLDSVLDTLLAPSGPGQSQPSPPACEVTSSWCLFGPELPEDPPAAPATQRVLSPLMSRSGCKVGDSSGTAAAHKVLPRGLSPARQLLLPASESPHWSGAPVKPSPQAAAVEVEEEDGSESEESAGPLLKGKPRALGGAAAGGGAAAVPPGAAAGGVALVPKEDSRFSAPRVALVEQDAPMAPGRSPLATTVM

种属同源性预测
宿主/亚型 Mouse / IgG1
抗体类别 Monoclonal
产品类型 Antibody
全称 progesterone receptor
别名 PGR, 3D1D12, NR3C3, PR, PRGR
计算分子量 933 aa, 99 kDa
GenBank蛋白编号NM_000926
基因名称 Progesterone Receptor
Gene ID (NCBI) 5241
RRIDAB_2881683
偶联类型 Unconjugated
形式Liquid
纯化方式Protein G purification
UNIPROT IDP06401
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

PGR (Progesterone Receptor), also named as NR3C3 and PR, belongs to the nuclear hormone receptor family and NR3 subfamily. The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. The ER and PR status has been used as a predictor of breast carcinoma responsiveness to endocrine therapy and as a prognostic indicator for early recurrence.