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验证数据展示

  • WB analysis of HEK-293 using 10060-1-AP (same clone as 10060-1-PBS)

    WB analysis of HEK-293 using 10060-1-AP (same clone as 10060-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10060-1-AP (FKBPL antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10060-1-PBS in a different storage buffer formulation.

  • IP experiment of MCF-7 using 10060-1-AP (same clone as 10060-1-PBS)

    IP experiment of MCF-7 using 10060-1-AP (same clone as 10060-1-PBS)

    IP result of anti-FKBPL (IP:10060-1-AP, 3ug; Detection:10060-1-AP 1:800) with MCF-7 cells lysate 2500ug. This data was developed using the same antibody clone with 10060-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 10060-1-AP (same clone as 10060-1-PBS)

    IHC staining of human breast cancer using 10060-1-AP (same clone as 10060-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10060-1-AP (FKBPL antibody) at dilution of 1:600 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10060-1-PBS in a different storage buffer formulation.

  • IHC staining of human breast cancer using 10060-1-AP (same clone as 10060-1-PBS)

    IHC staining of human breast cancer using 10060-1-AP (same clone as 10060-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human breast cancer tissue slide using 10060-1-AP (FKBPL antibody) at dilution of 1:600 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 10060-1-PBS in a different storage buffer formulation.

  • FC experiment of HeLa using 10060-1-AP (same clone as 10060-1-PBS)

    FC experiment of HeLa using 10060-1-AP (same clone as 10060-1-PBS)

    1x10^6 HeLa cells were intracellularly stained with 0.4 ug FKBPL Polyclonal antibody (10060-1-AP) and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) (SA00013-2)(red), or 0.4 ug Rabbit IgG control Rabbit PolyAb (30000-0-AP) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 10060-1-PBS in a different storage buffer formulation.

  • Featured Product
  • KD/KO验证

FKBPL Polyclonal antibody, PBS Only

FKBPL Polyclonal Antibody for WB, IHC, FC (Intra), IP, ELISA
Cat No. 10060-1-PBS

产品说明书

宿主/亚型

Rabbit / IgG

种属反应性

human

应用

WB, IHC, FC (Intra), IP, ELISA

别名

DIR1, FK506-binding protein-like, NG7, WAF-1/CIP1 stabilizing protein 39, WISp39

缓冲液配方:  PBS Only
PBS and Azide
PBS Only
偶联物:  Unconjugated
规格价格库存

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产品信息

10060-1-PBS targets FKBPL in WB, IHC, FC (Intra), IP, ELISA applications and shows reactivity with human samples.

经测试应用 WB, IHC, FC (Intra), IP, ELISA Application Description
经测试反应性 human
免疫原

CatNo: Ag0112

Product name: Recombinant human FKBPL protein

Source: e coli.-derived, PGEX-4T

Tag: GST

Domain: 2-237 aa of BC004168

Sequence: ETPPVNTIGEKDTSQPQQEWEKNLRENLDSVIQIRQQPRDPPTETLELEVSPDPASQILEHTQGAEKLVAELEGDSHKSHGSTSQMPEALQASDLWYCPDGSFVKKIVIRGHGLDKPKLGSCCRVLALGFPFGSGPPEGWTELTMGVGPWREETWGELIEKCLESMCQGEEAELQLPGHSGPPVRLTLASFTQGRDSWELETSEKEALAREERARGTELFRAGNPEGAARCYGRAL

种属同源性预测
宿主/亚型 Rabbit / IgG
抗体类别 Polyclonal
产品类型 Antibody
全称 FK506 binding protein like
别名 DIR1, FK506-binding protein-like, NG7, WAF-1/CIP1 stabilizing protein 39, WISp39
计算分子量 349 aa, 38 kDa
观测分子量 42-48 kDa
GenBank蛋白编号BC004168
基因名称 FKBPL
Gene ID (NCBI) 63943
RRIDAB_2262677
偶联类型 Unconjugated
形式Liquid
纯化方式Antigen affinity purification
UNIPROT IDQ9UIM3
储存缓冲液 PBS only, pH 7.3.
储存条件Store at -80°C.
The product is shipped with ice packs. Upon receipt, store it immediately at -80°C

背景介绍

FKBPL, also named as DIR1, NG7 and WISp39, has similarity to the immunophilin protein family, which plays a role in immunoregulation and basic cellular processes involving protein folding and trafficking. FKBPL levels may be a prognostic indicator and determinant of response to endocrine therapy(PMID:20103631, 15664193). It can be detected the band between 38 kDa and 48 kDa by western blot.